Effectiveness of Vitamin D in the Treatment of Mood Disorders: A Literature Review

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Depression is a mood disorder that has a significant negative impact on the lives of many individuals. Since vitamin D deficiency is prevalent in the North American population, recent scientific research is investigating the connection between insufficient vitamin D and the pathogenesis of mood disorders, as well as the nutrient’s potential as a therapeutic agent. Several epidemiological studies have shown a relationship between low levels of vitamin D and the presence of depression. A small number of intervention trials have found a potential trend toward the reduction of depressive symptoms from vitamin D supplementation; however, many of the studies had limitations which restrict the conclusions that can be drawn. Further research in the field is warranted.
Title of abstract: 
Effectiveness of Vitamin D in the Treatment of Mood Disorders: A Literature Review
Khamba B, Aucoin M, Tsirgielis D, Copeland A, Vermani M, Cameron C, Szpindel I, Laidlaw B, Epstein I, Katzman M
START Clinic for Mood and Anxiety Disorders, Department of Psychiatry University of Toronto, Department of Psychology Lakehead University, Northern Ontario School of Medicine, The Canadian College of Naturopathic Medicine
Friday, December 31, 2010
Journal of Orthomolecular Medicine, 2011, 26(3): 127:135

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