Natural Arthritis Pain Relief Study

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Osteoarthritis is a common, chronic joint condition that involves pain, stiffness and inflammation. This study is investigating the effectiveness of a natural cream at improving symptoms of arthritis of the knee. The cream contains rutin, a citrus flavonoid glycoside, and avocado and soybean phytosterols, which have anti-inflammatory properties. The study consists of 2 parts. The first part is 3 weeks long and placebo controlled – this means that you may receive the natural cream we are testing, or you may receive an inactive cream. The second part of the study is also 3 weeks long and all participants will try the natural cream.

Participant responsibilities:

The study consists of 1 screening visit and 6 follow-up visits at the clinic, plus the completion of some questionnaires in between visits. There will be 3 blood samples taken. You will be provided with a cream to apply twice per day for 6 weeks.

Exclusion criteria

  • Men or women of any age
  • Moderate-to-severe pain of the knee due to arthritis
  • Willing to avoid pain medication during the study
  • Not planning to become pregnant in the next two months
  • Current or ongoing use of homeopathic remedies within four weeks prior to enrolling in the study

Location of study:

The Canadian College of Naturopathic Medicine


Six weeks


$30 per visit (up to $210 total)


Athritis of the knee joint


Dr. Maria Shapoval, ND
647-557-6111 ext 420

Recruitment closed

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The Canadian College of Naturopathic Medicine

Educating naturopathic doctors in North America for over 40 years

1255 Sheppard Avenue East, Toronto, Ontario M2K 1E2

College: (416) 498-1255 I 1 (866) 241-2266 (toll-free)

Clinic: (416) 498-9763

Member of the Association of
Accredited Naturopathic Medical Colleges