An in vivo analysis of the herbal compound Essiac.

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BACKGROUND: Essiac is a herbal compound that has been in common use with cancer patients in North America for over 80 years. Despite its relatively widespread use, there are no peer-reviewed published reports of in vivo studies regarding the use of this compound.MATERIALS AND METHODS: Essiac was administered orally to test animals prior to all experiments. Standard assays to test protection from ethanol-induced gastric ulceration and carbon tetrachloride-induced hepatic injury were performed on Wistar rats. Assays of postglucose-load serum glucose and cellular and humoral immune modulation were conducted on ICR and BALB/C mice, respectively.RESULTS: Essiac demonstrated a modest gastric protective effect via reduction of ethanol-induced gastric ulceration. However, Essiac did not demonstrate significant hepatoprotective, hypoglycemic or immunomodulatory properties.CONCLUSION: Essiac, administered in established in vivo experimental models, did not significantly demonstrate its purported physiological modifying effects. PMID: 16886634
Title of abstract: 
An in vivo analysis of the herbal compound Essiac.
Author: 
Leonard BJ, Kennedy DA, Cheng FC, Chang KK, Seely D, Mills E.
Affiliations: 
University of Toronto, Canadian College of Naturopathic Medicine
Citedate: 
Saturday, December 31, 2005 - 19:00
Citation: 
Anticancer Research, 2006; 26(4B):3057-63.
Taxonomy: 
 

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