Abstracts

Intravenous Vitamin C in Cancer Care: Evidence Review and Practical Guidance for Integrative Oncology Practitioners

Abstract

Intravenous vitamin C (IVC) is a common therapy used by naturopathic doctors and other licensed integrative practitioners. With several proposed mechanisms of action related to cancer care, it is often used in integrative oncology settings. Despite its common use, there are no published evidence-based resources on the efficacy, safety, and procedural considerations for the use of IVC in practice.

Title of abstract:
Intravenous Vitamin C in Cancer Care: Evidence Review and Practical Guidance for Integrative Oncology Practitioners
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Abstracts

Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology–ASCO Guideline

Purpose:

To provide evidence-based recommendations to health care providers on integrative approaches to managing anxiety and depression symptoms in adults living with cancer.

Title of abstract:
Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology–ASCO Guideline
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Abstracts

Mistletoe Extracts during the Oncological Perioperative Period: A Systematic Review and Meta-Analysis of Human Randomized Controlled Trials

Background:

We aim to evaluate the safety and efficacy of mistletoe extract (ME) use during the oncological perioperative period. Methods: Details registered a priori on PROSPERO (CRD42018086168). Results: Seven RCTs (comprising 663 participants in nine reports) and three nonrandomized studies were included.

Title of abstract:
Mistletoe Extracts during the Oncological Perioperative Period: A Systematic Review and Meta-Analysis of Human Randomized Controlled Trials
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Abstracts

Vitamin C for the Treatment of Depression in Cancer Patients: A Literature Review

Introduction

One in two Canadians will be diagnosed with cancer in their lifetime and one in four will experience depression during their diagnosis. The cause of depression during cancer could be related to psychological, social, inflammatory, or immunological factors. Vitamin C can exert an effect on oxidative stress levels, adrenal function, and immune function and may have a role in the treatment of both cancer and depression.

Title of abstract:
Vitamin C for the Treatment of Depression in Cancer Patients: A Literature Review
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Abstracts

Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes After Cancer Treatment: A Study Protocol

Background:

Following cancer treatment, adults commonly report worsened patient-reported outcomes (PROs) such as anxiety, stress, depression, persistent and upsetting cognitive complaints, unrelenting fatigue, and reduced quality of life. Poorer PROs are associated with disrupted autonomic nervous system functioning as measured by heart rate variability (HRV), both of which have been associated with greater morbidity and mortality. Interventions to improve HRV and PROs among adults following cancer treatment are needed.

Title of abstract:
Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes After Cancer Treatment: A Study Protocol
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Abstracts

Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis.

Most observational studies show an association between melatonin and cancer in humans. We conducted a systematic review of randomized controlled trials (RCTs) of melatonin in solid tumor cancer patients and its effect on survival at 1 yr. With the aid of an information specialist, we searched 10 electronic databases from inception to October 2004. We included trials using melatonin as either sole treatment or as adjunct treatment. Pre-specified criteria guided our assessment of trial quality. We conducted a meta-analysis using a random effects model.

Title of abstract:
Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis.
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Abstracts

The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review.

BACKGROUND: Green tea is widely used by women for the prevention and treatment of breast cancer. The authors aimed to determine the efficacy of green tea ingestion on the risk of breast cancer development and the risk of breast cancer recurrence. METHODS: The authors conducted a systematic review and meta-analyses of observational studies from systematic searches of 8 electronic data sources and contact with authors. They included studies assessing breast cancer incidence and recurrence.

Title of abstract:
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review.
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Abstracts

An in vivo analysis of the herbal compound Essiac.

BACKGROUND: Essiac is a herbal compound that has been in common use with cancer patients in North America for over 80 years. Despite its relatively widespread use, there are no peer-reviewed published reports of in vivo studies regarding the use of this compound.MATERIALS AND METHODS: Essiac was administered orally to test animals prior to all experiments. Standard assays to test protection from ethanol-induced gastric ulceration and carbon tetrachloride-induced hepatic injury were performed on Wistar rats.

Title of abstract:
An in vivo analysis of the herbal compound Essiac.
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Abstracts

Metronomic dosing of chemotherapy: applications in pediatric oncology.

Pediatric cancer has a better outcome profile than adult cancers. However, refractory disease and the potential for long-term morbidity resulting from the use of conventional therapies necessitate the development of novel treatments for this population. Recent advances in oncology include the use of low dose metronomic (LDM) chemotherapy. The promise of this novel therapeutic approach includes reduced toxicity and the potential for efficacy predominantly through an antiangiogenic effect.

Title of abstract:
Metronomic dosing of chemotherapy: applications in pediatric oncology.
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Abstracts

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors.

BACKGROUND: Enrolling participants onto clinical trials of cancer presents an important challenge. We aimed to identify the concerns of patients with cancer about, and the barriers to, participation in clinical trials.METHODS: We did a systematic review to assess studies of barriers to participation in experimental trials and randomized trials for validity and content.

Title of abstract:
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors.
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