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DAVID W. LESCHEID B.Sc., PhD, ND

B.Sc. (Biology), Simon Fraser University, 1989
Diploma, Health & Fitness Studies, Simon Fraser University, 1989
PhD (Molecular Biology/Protein Chemistry), University of Victoria, 1997
ND, CCNM, 2002

Associate Professor, Basic Sciences

David Lescheid’s scholarly achievements were recognized with two graduation awards: the Founders Scholarship, for highest academic achievement throughout the four-year program and the Governor's Medal of Excellence, for outstanding academic and clinical performance. Dr. Lescheid joined the academic faculty at CCNM in September 2002. He is currently a full-time associate professor teaching medical microbiology and infectious disease as well as human physiology. He is also a supervising naturopathic doctor in CCNM's teaching clinic. In addition, Lescheid practises naturopathic medicine in an integrative health clinic in North York, Ontario.

Previous Appointments

1990-1997

University of Victoria lab instructor in third and fourth-year genetics, cell biology and animal physiology labs and lecturer in a fourth-year molecular endocrinology class.

University of Victoria research assistant in a molecular biology lab with experience in PCR, cloning, DNA sequencing, genomic library construction and screening, HPLC, RIA, and ELISA.

Selected Publications

Peer-Reviewed Journal Articles

Lescheid D.W., Johnstone B. 2003. Green Tea Polyphenols in Prostate Cancer Therapy. Journal of Integrative Medicine 1(2): 1-8 .

Somoza G.M., Lescheid D., Miranda L.A., Lo Nostro F.L., Magliulo-Cepriano L., Montaner A.D., Schreibman M.P., Rivier J.E., Sherwood N.M. 2002. Expression of pejerrey gonadotropin-releasing hormone (pjGnRH) in three orders of fish.  Biology of Reproduction 67(6):1864-71.

Adams B.A., Lescheid D.W., Vickers E.D., Crim L.W., Sherwood N.M 2002. Pituitary adenylate cyclase-activating polypeptide (PACAP) and growth hormone-releasing hormone-like peptide (GHRH) in sturgeon, whitefish, grayling, flounder and halibut: cDNA sequence, exon skipping and evolution. Regulatory Peptides 109: 27-37.    

Prousky, J.E., Lescheid D.W. 2002. The role of Vitamins B3 and C in the treatment of Histadelia. J. Orthomolecular Med.17: 17-21

Montaner A.D., Mongiat L., Lux-Lantos V.A.R., Park M.K., Fischer W.H., Craig A.G., Rivier J.E., Lescheid D., Lovejoy D., Libertum C., Sherwood N.M., Somoza G.M. 2001. Structure and biological activity of gonadotropin-releasing isoforms isolated from rat and hamster brains. Neuroendocrinology 74:202-212.

Cameron, C.B., Mackie, G.O. Powell, J.F.F., Lescheid, D.W., and Sherwood, N.M. 1999. Gonadotropin-releasing hormone in mulberry cells of Saccoglossus and Pytchodera (Hemichordata: Enteropneusta). Gen. Comp. Endocrinol 114: 2-10.

Lescheid, D.W., Schreibman, M.P., Magliulo-Cepriano, L., Warby, C.M. and Sherwood, N.M. 1998. A novel form of gonadotropin-releasing hormone (GnRH) is present in the brain of platyfish and green swordtail (Genus, Xiphophorus). Gen. Comp. Endocrinol. (submitted)

Lescheid, D.W., Teresawa, E., Abler, L.A., Urbanski, H.F., Warby, C.M., Millar, R.P and Sherwood, N.M. 1997. A second form of gonadotropin-releasing hormone with characteristics of chicken GnRH-II is present in the primate brain.
Endocrinology 138: 5618-5629.

Lescheid, D.W., Rosen, G.J., Bridge, E.A., Jones, R.E., Warby, C.M., and Sherwood, N.M. 1997. Immunoreactive gonadotropin-releasing hormone (GnRH) is detected only in the form of chicken GnRH-II within the brain of green anole, Anolis carolinensis. Gen. Comp. Endocrinol. 108: 247-257.

Lescheid, D.W., Powell, J.F.F. , Fischer,W.,Park, M, Craig, A., Bukovskaya, O., Barannikova, I.A. and Sherwood, N.M. 1995. Mammalian gonadotropin-releasing hormone (GnRH) identified by primary structure in Russian Sturgeon, Acipenser gueldenstaedti. Regulatory Peptides 55: 299-309.

Manuscripts in Progress

Lescheid DW Evidence based anti-microbial therapies in naturopathic medicine. 

Chapters in books

Sherwood, N.M., Lescheid, D.W. and von Schalburg, Kris. Origin and evolution of GnRH in vertebrates and invertebrates. 1997. GnRH Neurons: Gene to Behaviour. I.S. Parhar and Y. Sakuma (Eds.), Brain Shuppan Publishers, Tokyo, pp. 3-25.

Sherwood N.M., Parker D.B., McRory J.E., and Lescheid, D.W. Molecular evolution of growth hormone-releasing hormone and gonadotropin-releasing hormone. Fish Physiology, Vol. 13. N.M. Sherwood and C. Hew. (Eds.), Academic Press, U.S.A. 1994. pp. 3-66.

Patents

Sherwood, N.M, Parker, D.B, McRory, J.E., and Lescheid, D.W. DNA encoding two fish neuropeptides. U.S. Patent number 5695954. Issue date: 12/09/1997

Presentations at Scientific Meetings

Endocrine Society Meetings, June 11-15, 1996. San Francisco, California. A second form of gonadotropin-releasing hormone ,GnRH, in primate brain. D.W. Lescheid, E. Teresawa, C. Quanbeck, H.F., Urbanski, C.M. Warby, and N.M. Sherwood.

Society for Neuroscience Annual Meeting, Nov. 13-18,1994, Miami Beach, Florida. Evolution of fish brain neuropeptides. Sherwood, N.M., Powell, J.F.F., McRory, J.E., Lescheid, D.W., Von Schalburg, K.

IUBS Symposium on Advances in the Molecular Endocrinology of Fish. May 23-25, 1993. Toronto, Canada. Molecular evolution of growth hormone-releasing hormone and PACAP. Sherwood N.M., Parker D.B., McRory J.E., and Lescheid D.W. p1

XII International Congress of Comparative Endocrinology. May 16-21, 1993. Toronto, Canada. Growth hormone-releasing hormone (GHRH) pituitary adenylate cyclase activating polypeptide (PACAP) cDNAs of salmon, catfish and sturgeon. Parker D.B., McRory J.E., Lescheid D.W., and N.M. Sherwood.

Symposium on Advances in the Molecular Endocrinology of Fish. Parker D.B., McRory J.E., Lescheid, D. and Sherwood, N.M. Molecular cloning of the fish growth hormone-releasing hormone (GHRH)- like peptide and pituitary adenylate cyclase activating peptide (PACAP) cDNAs and gene.

IUBS Symposium on Advances in the Molecular Endocrinology of Fish. May 17-19, 1997. Toronto, Canada. The GRF/PACAP gene: evolution and expression. Sherwood N.M., McRory J.E., Lescheid D.W., Krueckl, S.L., and Fradinger, E. p.1

5th International Symposium on VIP, PACAP, Secretin, Glucagon and Related peptides. Nov. 4-8, 2001. Santa Barbara, CA, USA. Clues to PACAP evolution and function from fish. Adams B.A., Krueckl S.L., Lescheid D.W., Vickers E.D., Sherwood N.M.
 

Recent Awards

NSA most appreciated instructor award CCNM, 2003
Founder's Scholarship 2002 (highest academic achievement, CCNM, 1998-2002)
Governor General's Award 2002 (Clinical and Academic Excellence)
Christopher Leadership Pin 2002 (exemplary leadership qualities)
The 1996 CORNING Nichols new investigator travel award
Graduate Teaching Fellowship 1996, 1995, 1993/1994, 1991/1992
The Randy Baker Memorial Fellowship 1993/1994
The Maureen DeBurgh Fellowship 1993/1994
King Platt Memorial Award 1993/1994
King Platt Fellowship 1992/1993
W. Gordon Fields Memorial Fellowship 1990/1991
All-Canadian Academic Award 1990/ 1991

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