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DAVID
W. LESCHEID
B.Sc., PhD, ND
B.Sc. (Biology),
Simon Fraser University, 1989
Diploma, Health & Fitness Studies, Simon Fraser University,
1989
PhD (Molecular Biology/Protein Chemistry), University of Victoria,
1997
ND, CCNM, 2002
Associate Professor, Basic Sciences
David Lescheid’s scholarly
achievements were recognized with two graduation awards: the
Founders Scholarship, for highest academic achievement throughout
the four-year program and the Governor's Medal of Excellence, for
outstanding academic and clinical performance. Dr. Lescheid joined
the academic faculty at CCNM in September 2002. He is currently a
full-time associate professor teaching medical microbiology and
infectious disease as well as human physiology. He is also a
supervising naturopathic doctor in CCNM's teaching clinic. In
addition, Lescheid practises naturopathic medicine in an integrative
health clinic in North York, Ontario.
Previous Appointments
1990-1997
University of Victoria lab
instructor in third and fourth-year genetics, cell biology and
animal physiology labs and lecturer in a fourth-year molecular
endocrinology class.
University of Victoria research assistant in a
molecular biology lab with experience in PCR, cloning, DNA
sequencing, genomic library construction and screening, HPLC, RIA,
and ELISA.
Selected
Publications
Peer-Reviewed Journal Articles
Lescheid D.W., Johnstone B. 2003.
Green Tea Polyphenols in Prostate Cancer Therapy. Journal of
Integrative Medicine 1(2): 1-8 .
Somoza G.M., Lescheid D., Miranda
L.A., Lo Nostro F.L., Magliulo-Cepriano L., Montaner A.D.,
Schreibman M.P., Rivier J.E., Sherwood N.M. 2002. Expression of
pejerrey gonadotropin-releasing hormone (pjGnRH) in three orders of
fish. Biology of Reproduction 67(6):1864-71.
Adams B.A., Lescheid D.W., Vickers
E.D., Crim L.W., Sherwood N.M 2002. Pituitary adenylate cyclase-activating
polypeptide (PACAP) and growth hormone-releasing hormone-like
peptide (GHRH) in sturgeon, whitefish, grayling, flounder and
halibut: cDNA sequence, exon skipping and evolution. Regulatory
Peptides 109: 27-37.
Prousky, J.E., Lescheid D.W. 2002.
The role of Vitamins B3 and C in the treatment of Histadelia. J.
Orthomolecular Med.17: 17-21
Montaner A.D., Mongiat L.,
Lux-Lantos V.A.R., Park M.K., Fischer W.H., Craig A.G., Rivier J.E.,
Lescheid D., Lovejoy D., Libertum C., Sherwood N.M., Somoza G.M.
2001. Structure and biological activity of gonadotropin-releasing
isoforms isolated from rat and hamster brains. Neuroendocrinology
74:202-212.
Cameron, C.B., Mackie, G.O. Powell,
J.F.F., Lescheid, D.W., and Sherwood, N.M. 1999. Gonadotropin-releasing
hormone in mulberry cells of Saccoglossus and Pytchodera
(Hemichordata: Enteropneusta). Gen. Comp. Endocrinol 114:
2-10.
Lescheid, D.W., Schreibman, M.P.,
Magliulo-Cepriano, L., Warby, C.M. and Sherwood, N.M. 1998. A novel
form of gonadotropin-releasing hormone (GnRH) is present in the
brain of platyfish and green swordtail (Genus, Xiphophorus).
Gen. Comp. Endocrinol. (submitted)
Lescheid, D.W., Teresawa, E.,
Abler, L.A., Urbanski, H.F., Warby, C.M., Millar, R.P and Sherwood,
N.M. 1997. A second form of gonadotropin-releasing hormone with
characteristics of chicken GnRH-II is present in the primate brain.
Endocrinology 138: 5618-5629.
Lescheid, D.W., Rosen, G.J.,
Bridge, E.A., Jones, R.E., Warby, C.M., and Sherwood, N.M. 1997.
Immunoreactive gonadotropin-releasing hormone (GnRH) is detected
only in the form of chicken GnRH-II within the brain of green anole,
Anolis carolinensis. Gen. Comp. Endocrinol. 108: 247-257.
Lescheid, D.W., Powell, J.F.F. ,
Fischer,W.,Park, M, Craig, A., Bukovskaya, O., Barannikova, I.A. and
Sherwood, N.M. 1995. Mammalian gonadotropin-releasing hormone (GnRH)
identified by primary structure in Russian Sturgeon, Acipenser
gueldenstaedti. Regulatory Peptides 55: 299-309.
Manuscripts in Progress
Lescheid DW Evidence based
anti-microbial therapies in naturopathic medicine.
Chapters in books
Sherwood, N.M., Lescheid, D.W. and
von Schalburg, Kris. Origin and evolution of GnRH in vertebrates and
invertebrates. 1997. GnRH Neurons: Gene to Behaviour. I.S.
Parhar and Y. Sakuma (Eds.), Brain Shuppan Publishers, Tokyo, pp.
3-25.
Sherwood N.M., Parker D.B., McRory
J.E., and Lescheid, D.W. Molecular evolution of growth
hormone-releasing hormone and gonadotropin-releasing hormone.
Fish Physiology, Vol. 13. N.M. Sherwood and C. Hew. (Eds.),
Academic Press, U.S.A. 1994. pp. 3-66.
Patents
Sherwood, N.M, Parker,
D.B, McRory, J.E., and Lescheid, D.W. DNA encoding two fish neuropeptides.
U.S. Patent number 5695954. Issue date: 12/09/1997
Presentations
at Scientific Meetings
Endocrine Society Meetings, June
11-15, 1996. San Francisco, California. A second form of
gonadotropin-releasing hormone ,GnRH, in primate brain. D.W.
Lescheid, E. Teresawa, C. Quanbeck, H.F., Urbanski, C.M. Warby, and
N.M. Sherwood.
Society for Neuroscience Annual
Meeting, Nov. 13-18,1994, Miami Beach, Florida. Evolution of fish
brain neuropeptides. Sherwood, N.M., Powell, J.F.F., McRory, J.E.,
Lescheid, D.W., Von Schalburg, K.
IUBS Symposium on Advances in
the Molecular Endocrinology of Fish. May 23-25, 1993. Toronto,
Canada. Molecular evolution of growth hormone-releasing hormone and
PACAP. Sherwood N.M., Parker D.B., McRory J.E., and Lescheid D.W. p1
XII International Congress of
Comparative Endocrinology. May 16-21, 1993. Toronto, Canada. Growth
hormone-releasing hormone (GHRH) pituitary adenylate cyclase
activating polypeptide (PACAP) cDNAs of salmon, catfish and
sturgeon. Parker D.B., McRory J.E., Lescheid D.W., and N.M.
Sherwood.
Symposium on Advances in the
Molecular Endocrinology of Fish. Parker D.B., McRory J.E.,
Lescheid, D. and Sherwood, N.M. Molecular cloning of the fish growth
hormone-releasing hormone (GHRH)- like peptide and pituitary
adenylate cyclase activating peptide (PACAP) cDNAs and gene.
IUBS Symposium on Advances in
the Molecular Endocrinology of Fish. May 17-19, 1997. Toronto,
Canada. The GRF/PACAP gene: evolution and expression. Sherwood N.M.,
McRory J.E., Lescheid D.W., Krueckl, S.L., and Fradinger, E. p.1
5th International Symposium on VIP,
PACAP, Secretin, Glucagon and Related peptides. Nov. 4-8, 2001.
Santa Barbara, CA, USA. Clues to PACAP evolution and function from
fish. Adams B.A., Krueckl S.L., Lescheid D.W., Vickers E.D.,
Sherwood N.M.
Recent Awards
NSA most appreciated instructor
award CCNM, 2003
Founder's Scholarship 2002 (highest
academic achievement, CCNM, 1998-2002)
Governor General's Award
2002 (Clinical and Academic Excellence)
Christopher Leadership Pin 2002 (exemplary leadership qualities)
The 1996 CORNING Nichols new investigator travel award
Graduate Teaching Fellowship 1996, 1995, 1993/1994, 1991/1992
The Randy Baker Memorial Fellowship 1993/1994
The Maureen DeBurgh Fellowship 1993/1994
King Platt Memorial Award 1993/1994
King Platt Fellowship 1992/1993
W. Gordon Fields Memorial Fellowship 1990/1991
All-Canadian Academic Award 1990/ 1991
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