- Prospective Students
- Why choose CCNM?
- Admissions Information
- How to Apply
- Student Life
- ND Program
- Bridge Delivery for IMGs
- Tuition and Fees
- Financial Assistance
- Fragrance-free Policy
- Our Clinics
- Practice Management
EDTA chelation therapy for cardiovascular disease: a systematic review.
Citation:Seely DM, Wu P, Mills EJ. BMC Cardiovascular Disorders, 2005;5:32.
BACKGROUND: Numerous practitioners of both conventional and complementary and alternative medicine throughout North America and Europe claim that chelation therapy with EDTA is an effective means to both control and treat cardiovascular disease. These claims are controversial, and several randomized controlled trials have been completed dealing with this topic. To address this issue we conducted a systematic review to evaluate the best available evidence for the use of EDTA chelation therapy in the treatment of cardiovascular disease.
METHODS: We conducted a systematic review of 7 databases from inception to May 2005. Hand searches were conducted in review articles and in any of the trials found. Experts in the field were contacted and registries of clinical trials were searched for unpublished data. To be included in the final systematic review, the studies had to be randomized controlled clinical trials.
RESULTS: A total of seven articles were found assessing EDTA chelation for the treatment of cardiovascular disease. Two of these articles were subgroup analyses of one RCT that looked at different clinical outcomes. Of the remaining five studies, two smaller studies found a beneficial effect whereas the other three exhibited no benefit for cardiovascular disease from the use of EDTA chelation therapy. Adverse effects were rare but those of note included a few cases of hypocalcemia and a single case of increased creatinine in a patient on the EDTA intervention.
CONCLUSION: The best available evidence does not support the therapeutic use of EDTA chelation therapy in the treatment of cardiovascular disease. Although not considered to be a highly invasive or harmful therapy, it is possible that the use of EDTA chelation therapy in lieu of proven therapy may result in causing indirect harm to the patient.
- News & Events
- Participate in Clinical Trials
- Primary Research: Clinical Trials
- Secondary Synthesis Research
- Peer-reviewed Publications
- . .
- A comparative review of thermography as a breast cancer screening technique.
- A systematic review of the safety and efficacy of common and cassia cinnamon bark for type 2 diabetes
- Acupuncture for treatment of HIV associated acute inflammatory demyelinating polyradiculoneuropathy
- Acupuncture in Poststroke Rehabilitation
- African herbal medicines in the treatment of HIV
- An in vivo analysis of the herbal compound Essiac.
- Barriers to participation in clinical trials of cancer
- Cost Effectiveness of Natural Health Products
- Cost-effectiveness of naturopathic care for chronic low back pain
- EDTA chelation therapy for cardiovascular disease
- Effectiveness of smoking cessation therapies
- Efficacy of acupuncture for cocaine dependence
- In vitro analysis of the herbal compound Essiac.
- Integrative practices of Canadian oncology health professionals
- Interactions of natural health products with biomedical cancer treatments
- Knowledge of safety and herb-drug interations amongst HIV+ individuals
- Links between ADHD and Environmental Pollutants
- Melatonin in the treatment of cancer
- Metronomic dosing of chemotherapy: applications in pediatric oncology
- Naturopathic Care for Anxiety
- Orthomolecular Treatment of Anxiety Disorders
- Orthomolecular and Botanical Treatments to Help Alleviate the Side Effects of Atypical Antipsychotic Drugs
- Patient decision-making about complementary and alternative medicine in cancer
- Pellagra may be a rare secondary complication of anorexia nervosa
- Strategy for controlling potential interactions between natural health products and chemotherapy
- The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer
- Research Faculty
- Research Partnerships
- Integrative Cancer Care
- Learning resources Centre
- Alumni Services
- Continuing Education
- Current Students
- Human Resources
- WAYS TO GIVE